In 1998, ASE 11.9.2 was rolled out with support for data pages locking, data rows (row-level locking), distributed joins and improved SMP performance. The Logical Process Manager was added to allow prioritization by assigning execution attributes and engine affinity. Sybase 11.5 added Asynchronous prefetch, case expression in sql, the optimizer can use a descending index to avoid the need for a worktable and a sort. Starting with version 11.5 released in 1996, Sybase moved to differentiate its product from Microsoft SQL Server by renaming it to Adaptive Server Enterprise. In 1995, Sybase released SQL Server 11.0. Version 10 and onwards uses CTLIB (ClienT LIBrary). Prior to version 10, DBLIB (DataBase LIBrary) was used. Sybase provides native low-level programming interfaces to its database server which uses a protocol called Tabular Data Stream. Microsoft continued on with Microsoft SQL Server. Sybase released Sybase SQL Server 10.0, which was part of the System 10 product family, which also included Back-up Server, Open Client/Server APIs, SQL Monitor, SA Companion and OmniSQL Gateway. In 1993, the co-development licensing agreement between Microsoft and Sybase ended, and the companies parted ways while continuing to develop their respective versions of SQL Server.

This release included internationalization and localization and support for symmetric multiprocessing systems. Microsoft and Sybase sold and supported the product through version 4.2.1. Ashton-Tate divested its interest and Microsoft became the lead partner after porting SQL Server to Windows NT. In 1988, SQL Server for OS/2 was co-developed for the PC by Sybase, Microsoft, and Ashton-Tate. Originally developed for Unix operating system platforms in 1987, Sybase Corporation's primary relational database management system product was initially marketed under the name Sybase SQL Server.

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